Proteomic analysis of the cerebrospinal fluid of patients with restless legs syndrome/Willis-Ekbom disease
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چکیده
منابع مشابه
Treatment of restless legs syndrome/Willis-Ekbom disease with selenium
Restless legs syndrome/Willis-Ekbom disease (RLS/WED) is a chronic neurosensory disorder that is characterized by a strong urge to move, accompanied by an uncomfortable paresthesia in the legs which affects about 5-15 percent of adult people in industrialized countries.1 RLS/WED is a puzzling disease, mostly because of the uncertainty of its etiology. There seems to be a genetic component, but ...
متن کاملMood disorders in restless legs syndrome (Willis-Ekbom disease).
OBJECTIVE Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is a sensorimotor disorder that can result in considerable sleep disruption. This narrative review provides an overview of RLS diagnosis and reports epidemiologic evidence for an association between RLS and mood disorders. Possible links between RLS, sleep disturbances, and mood disorders are considered, and theoretical...
متن کاملRestless Legs Syndrome (Willis-Ekbom Disease) and Gastrointestinal Diseases
Over 50 diseases, disorders and conditions have been reported to be associated and/or contribute to restless legs syndrome (RLS) (recently renamed Willis-Ekbom disease). In many of these diseases, disorders and conditions is the potential to have systemic inflammation or immune disorders. In addition, in some of the idiopathic syndromes and diseases, there is an underlying gut dysfunction with ...
متن کاملProteomic analysis of the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
So far, only the detection of 14-3-3 proteins in cerebrospinal fluid (CSF) has been accepted as diagnostic criterion for Creutzfeldt-Jakob disease (CJD). However, this assay cannot be used for screening because of the high rate of false-positive results, whereas patients with variant CJD are often negative for 14-3-3 proteins. The aim of this study was to compare the spot patterns of CSF by 2-d...
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ژورنال
عنوان ژورنال: Fluids and Barriers of the CNS
سال: 2013
ISSN: 2045-8118
DOI: 10.1186/2045-8118-10-20